2024 Phenolphthaleins

Phenolphthaleins

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August undefined, 2024

WebBackground: Phenolphthalein is widely used as a safe and effective laxative. After oral administration, phenolphthalein is absorbed in the small bowel and is conjugated in the … Web1. Biliary elimination in female Wistar albino rats 3 h after i.p. injection of [3H]phenolphthalein, [3H]morphine, 14C-LSD and [14C]diphenylacetic acid was 90%, 45%, …

Phenolphthalein exposure causes multiple carcinogenic effects in ...

WebPhenolphthalein, the active ingredient in many laxatives, was recently found to be a carcinogen in animal models. Human data suggest a laxative-colon cancer association, … WebPhenolphthaleins synonyms, Phenolphthaleins pronunciation, Phenolphthaleins translation, English dictionary definition of Phenolphthaleins. n. A white or pale yellow crystalline powder, C20H14O4, used as an acid-base indicator, in making dyes, and formerly in medicine as an over-the-counter... taj outline graphic

Metabolism and disposition of phenolphthalein in male and

Web2. A process of producing phenolphthalein which consists in heating a mixture of phenol and phthalic anhydride in the presence of anhydrous zinc chloride, adding to the mixture anhydrous aluminum chloride, continuing the heating of the mixture whilst stirring the same, and removing the zinc chloride, aluminum chloride, unreacted phenol and ... WebThe therapeutic response and side effect profile of the different doses favoured 30 mg phenolphthalein as the optimum laxative dose. Although theoretically superior, phenolphthalein glucuronide was not found to be a more effective laxative compared to phenolphthalein in normal subjects. WebBackground: Fiber and water-holding agents are used for the treatment of constipation. In what may appear to be a paradox, they are sometimes also used for the treatment of diarrhea; it has been proposed that they sequester water from liquid stools and/or increase the ratio of fecal solids to fecal water and thereby improve stool consistency. basler winterjacken damen

US1940146A - Process of purifying phenolphthalein - Google

Phenolphthaleins

WebIn response to this finding the metabolism and disposition of PHTH has been evaluated in both F344 rats and B6C3F1 mice at a single oral dose of 800 mg/kg. This dose fell within the range previously found to be carcinogenic in rats and mice. Studies were also performed using 1 and 50 mg/kg doses. At 800 mg/kg recovery of [14C]PHTH after 72 h ... WebGet the latest COVID-19 technical guidance, scientific and policy briefs here.

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Web11.05 - Verhalten von Seifenlösungen. Beim Auflösen in Wasser reagiert Schmierseife alkalisch, wie die rot-violette Färbung des Phenolphthaleins andeutet. Zugabe von Säure erzeugt die entsprechende Carbonsäure. Das Phenolphthalein entfärbt sich und die entstehende Carbonsäure, die nicht mehr wasserlöslich ist, trübt die Lösung. Web15. apr 1998 · While chains of hydrogen bonds propagate in a number of directions in this structure, cyclic hydrogen bonding is not observed. 3',3"-Dinitrophenolphthalein, …

WebA system for expression cloning of bacterial phosphatase-encoding genes has been developed, and its potential has been investigated. The system is based on histochemical screening of bacterial genomic libraries, constructed in an Escherichia coli multicopy plasmid vector, for phosphatase-producing clones using an indicator medium (named … WebIn the process for the preparation of phenolphthalein the step comprising the reaction of phenol with phthalic anhydride in the presence of zinc chloride and from about 0.05 to …

WebA recent 2-year carcinogenicity/toxicology study determined that phenolphthalein (PHTH) is a multisite carcinogen in both mice and rats at all doses evaluated. In response to this … WebAs nouns the difference between phenolphthalein and phenol. is that phenolphthalein is a quinone derivative used as a pH indicator, and once used as a laxative while phenol is a caustic, poisonous, white crystalline compound, C 6 H 5 OH, derived from benzene and used in resins, plastics, and pharmaceuticals and in dilute form as a disinfectant ...

Web10. mar 2024 · phenolphthalein ( countable and uncountable, plural phenolphthaleins ) ( chemistry, pharmacology) A white or yellowish -white crystalline compound C 20 H 14 O 4 used in medicine as a laxative and in analysis as an indicator because its solution is brilliant red in alkalies and is decolorized by acids.

WebPhenolphthalein, the active ingredient in many laxatives, was recently found to be a carcinogen in animal models. Human data suggest a laxative-colon cancer association, but few data specifically address the effects of phenolthalein-containing laxatives. We examined use of phenolphtalein-containing … baslieal mesfin sebagads bas lesemanWebPhenolphthaleins Accession Number DBCAT001620 Description. A family of 3,3-bis(p-hydroxyphenyl)phthalides. They are used as CATHARTICS, indicators, and COLORING AGENTS. Drugs. Drug Drug Description; Phenolphthalein: A drug used for symptomatic relief of constipation and bowel cleansing prior to medical procedures. basler zeitung zakariaWebPhenolphthaleins / administration & dosage Phenolphthaleins / toxicity* Pregnancy Reproduction / drug effects* Seminiferous Tubules / drug effects Seminiferous Tubules / pathology Sperm Count / drug effects Spermatozoa / abnormalities ... taj p24 jamaicaWebIn this study, phenolphthaleins have been introduced into hybrid tetraarylethylene bridged six-membered benzene rings and five-membered thiophene rings to construct new multifunctional molecules responding to UV/Vis light, acid/base and water. Results showed that the titled molecules exhibited distinctive photochromism and acid-base discoloration … baslev timburhandilWebIn this study, phenolphthaleins have been introduced into hybrid tetraarylethylene bridged six-membered benzene rings and five-membered thiophene rings to construct new multifunctional molecules responding to UV/Vis light, acid/base and water. Results showed that the titled molecules exhibited distinctive photochromism and acid-base discoloration … baslik guWebThe meaning of PHENOLPHTHALEIN is a white or yellowish-white crystalline compound C20H14O4 used in analysis as an indicator because its solution is brilliant red in alkalies … taj opera