網頁2024年12月5日 · The Human Cell Atlas Project is an international collabor … The recent advent of methods for high-throughput single-cell molecular profiling has catalyzed a … 網頁2024年3月6日 · The cell type atlas was created based on the combination of two single-cell-level, whole-brain-scale datasets: a single- cell RNA-sequencing (scRNA-seq) dataset of ∼7 million cells profiled, and a spatially resolved transcriptomic dataset of ∼4.3 million cells using MERFISH. The atlas is hierarchically organized into five nested levels of ...

The Human Cell Atlas: from vision to reality Nature

網頁2024年11月17日 · As cell type annotation varies wildly across the datasets used in our atlas construction, we harmonized the cell type labels with our own automatic cell type annotation tool. For successful automatic cell type annotation, a high quality cell type reference database is necessary. auto maarssen

人类细胞图谱（HCA）计划：大型、权威的单细胞测序数据来源

網頁The Human Protein Atlas project launched the Cell Atlas in 2016. This open-source database provides high-resolution insights into the spatial-temporal distribution of proteins in each organelle. Within the Cell Atlas, the subcellular localization of >12,000 proteins is mapped on a single-cell level to 33 organelles, enabling the definition of ... 網頁1 天前 · Credit: Pixabay/CC0 Public Domain. Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled—a scientific … 網頁2024年6月16日 · Here we describe a single-cell atlas of aging for the nematode Caenorhabditis elegans. This unique resource describes the expression across adulthood of over 20,000 genes among 211 groups of cells that correspond to virtually every cell type in this organism. Our findings suggest that C. elegans aging is not random and stochastic in … auto mall 2000 houston tx